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Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin
As one of the most complex post-translational modification, glycosylation is widely involved in cell adhesion, cell proliferation and immune response. Nevertheless glycoproteins with an identical polypeptide backbone mostly differ in their glycosylation patterns. Due to this heterogeneity, the mappi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986796/ https://www.ncbi.nlm.nih.gov/pubmed/29867209 http://dx.doi.org/10.1038/s41598-018-26936-x |