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Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin

As one of the most complex post-translational modification, glycosylation is widely involved in cell adhesion, cell proliferation and immune response. Nevertheless glycoproteins with an identical polypeptide backbone mostly differ in their glycosylation patterns. Due to this heterogeneity, the mappi...

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Detalles Bibliográficos
Autores principales: Zemella, Anne, Thoring, Lena, Hoffmeister, Christian, Šamalíková, Mária, Ehren, Patricia, Wüstenhagen, Doreen A., Kubick, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986796/
https://www.ncbi.nlm.nih.gov/pubmed/29867209
http://dx.doi.org/10.1038/s41598-018-26936-x