Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing

Laminin, as a key component of the basement membrane extracellular matrix (ECM), regulates tissue morphogenesis. Here, we show that multiple laminin isoforms promiscuously bind to growth factors (GFs) with high affinity, through their heparin-binding domains (HBDs) located in the α chain laminin-typ...

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Detalles Bibliográficos
Autores principales: Ishihara, Jun, Ishihara, Ako, Fukunaga, Kazuto, Sasaki, Koichi, White, Michael J. V., Briquez, Priscilla S., Hubbell, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986797/
https://www.ncbi.nlm.nih.gov/pubmed/29867149
http://dx.doi.org/10.1038/s41467-018-04525-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986797/
https://www.ncbi.nlm.nih.gov/pubmed/29867149
http://dx.doi.org/10.1038/s41467-018-04525-w

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