Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis

Copious evidence demonstrates the crucial role of Rho GTPase-activating proteins in human malignancies. The downregulation of Rho GTPase-activating protein 15 (ARHGAP15), a Rac1-specific GAP, has been observed in glioma and pancreatic ductal adenocarcinoma. The present study explored the expression...

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Detalles Bibliográficos
Autores principales: Pan, Shengli, Deng, Yingying, Fu, Jun, Zhang, Yuhao, Zhang, Zhijin, Ru, Xiaokun, Qin, Xianju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986807/
https://www.ncbi.nlm.nih.gov/pubmed/29867200
http://dx.doi.org/10.1038/s41419-018-0707-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986807/
https://www.ncbi.nlm.nih.gov/pubmed/29867200
http://dx.doi.org/10.1038/s41419-018-0707-6

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