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Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo

Recent evidence suggests that the accumulation of macrophages as a result of obesity-induced adipose tissue hypoxia is crucial for the regulation of tissue fibrosis, but the molecular mechanisms underlying adipose tissue fibrosis are still unknown. In this study, we revealed that periostin (Postn) i...

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Detalles Bibliográficos
Autores principales: Nakazeki, Fumiko, Nishiga, Masataka, Horie, Takahiro, Nishi, Hitoo, Nakashima, Yasuhiro, Baba, Osamu, Kuwabara, Yasuhide, Nishino, Tomohiro, Nakao, Tetsushi, Ide, Yuya, Koyama, Satoshi, Kimura, Masahiro, Tsuji, Shuhei, Sowa, Naoya, Yoshida, Shigeo, Conway, Simon J., Yanagita, Motoko, Kimura, Takeshi, Ono, Koh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986813/
https://www.ncbi.nlm.nih.gov/pubmed/29867212
http://dx.doi.org/10.1038/s41598-018-27009-9