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Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo
Recent evidence suggests that the accumulation of macrophages as a result of obesity-induced adipose tissue hypoxia is crucial for the regulation of tissue fibrosis, but the molecular mechanisms underlying adipose tissue fibrosis are still unknown. In this study, we revealed that periostin (Postn) i...
Autores principales: | Nakazeki, Fumiko, Nishiga, Masataka, Horie, Takahiro, Nishi, Hitoo, Nakashima, Yasuhiro, Baba, Osamu, Kuwabara, Yasuhide, Nishino, Tomohiro, Nakao, Tetsushi, Ide, Yuya, Koyama, Satoshi, Kimura, Masahiro, Tsuji, Shuhei, Sowa, Naoya, Yoshida, Shigeo, Conway, Simon J., Yanagita, Motoko, Kimura, Takeshi, Ono, Koh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986813/ https://www.ncbi.nlm.nih.gov/pubmed/29867212 http://dx.doi.org/10.1038/s41598-018-27009-9 |
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