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Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?

DNA damage causes a local distortion of chromatin that triggers the sequential processes that participate in specific DNA repair mechanisms. This initiation of the repair response requires the involvement of a protein whose activity can be regulated by histones. Kinases are candidates to regulate an...

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Detalles Bibliográficos
Autores principales: Campillo-Marcos, Ignacio, Lazo, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986855/
https://www.ncbi.nlm.nih.gov/pubmed/29679095
http://dx.doi.org/10.1007/s00018-018-2811-2