Cargando…
Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?
DNA damage causes a local distortion of chromatin that triggers the sequential processes that participate in specific DNA repair mechanisms. This initiation of the repair response requires the involvement of a protein whose activity can be regulated by histones. Kinases are candidates to regulate an...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986855/ https://www.ncbi.nlm.nih.gov/pubmed/29679095 http://dx.doi.org/10.1007/s00018-018-2811-2 |