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Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?
DNA damage causes a local distortion of chromatin that triggers the sequential processes that participate in specific DNA repair mechanisms. This initiation of the repair response requires the involvement of a protein whose activity can be regulated by histones. Kinases are candidates to regulate an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986855/ https://www.ncbi.nlm.nih.gov/pubmed/29679095 http://dx.doi.org/10.1007/s00018-018-2811-2 |