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The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography
The effect of a mutation on the organism often depends on what other mutations are already present in its genome. Geneticists refer to such mutational interactions as epistasis. Pairwise epistatic effects have been recognized for over a century, and their evolutionary implications have received theo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986866/ https://www.ncbi.nlm.nih.gov/pubmed/29904213 http://dx.doi.org/10.1007/s10955-018-1975-3 |