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Cross-talk among HMGA1 and FoxO1 in control of nuclear insulin signaling

As a mediator of insulin-regulated gene expression, the FoxO1 transcription factor represents a master regulator of liver glucose metabolism. We previously reported that the high-mobility group AT-hook 1 (HMGA1) protein, a molecular switch for the insulin receptor gene, functions also as a downstrea...

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Detalles Bibliográficos
Autores principales: Chiefari, Eusebio, Arcidiacono, Biagio, Palmieri, Camillo, Corigliano, Domenica Maria, Morittu, Valeria Maria, Britti, Domenico, Armoni, Michal, Foti, Daniela Patrizia, Brunetti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986867/
https://www.ncbi.nlm.nih.gov/pubmed/29867121
http://dx.doi.org/10.1038/s41598-018-26968-3