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Pathogenesis of Skin Carcinomas and a Stem Cell as Focal Origin

UV radiation in sunlight has long been recognized as the main exogenous cause of skin carcinomas. We present a brief historical perspective on the progress in understanding the pathogenesis of skin carcinomas, and recent advances. Sun-exposed skin carries numerous UV-related mutations, and skin carc...

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Detalles Bibliográficos
Autores principales: de Gruijl, Frank R., Tensen, Cornelis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986939/
https://www.ncbi.nlm.nih.gov/pubmed/29896477
http://dx.doi.org/10.3389/fmed.2018.00165