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Hypoxic Signalling in Tumour Stroma

Hypoxia is a common feature in solid tumors and is associated with cancer progression. The main regulators of the hypoxic response are hypoxia-inducible transcription factors (HIFs) that guide the cellular adaptation to hypoxia by gene activation. The actual oxygen sensing is performed by HIF prolyl...

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Detalles Bibliográficos
Autores principales: Laitala, Anu, Erler, Janine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986951/
https://www.ncbi.nlm.nih.gov/pubmed/29896451
http://dx.doi.org/10.3389/fonc.2018.00189