Protein Deiminase 4 and CR3 Regulate Aspergillus fumigatus and β-Glucan-Induced Neutrophil Extracellular Trap Formation, but Hyphal Killing Is Dependent Only on CR3

Neutrophil extracellular trap (NET) formation requires chromatin decondensation before nuclear swelling and eventual extracellular release of DNA, which occurs together with nuclear and cytoplasmic antimicrobial proteins. A key mediator of chromatin decondensation is protein deiminase 4 (PAD4), whic...

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Detalles Bibliográficos
Autores principales: Clark, Heather L., Abbondante, Serena, Minns, Martin S., Greenberg, Elyse N., Sun, Yan, Pearlman, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986955/
https://www.ncbi.nlm.nih.gov/pubmed/29896200
http://dx.doi.org/10.3389/fimmu.2018.01182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986955/
https://www.ncbi.nlm.nih.gov/pubmed/29896200
http://dx.doi.org/10.3389/fimmu.2018.01182

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