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Condition-Specific Modeling of Biophysical Parameters Advances Inference of Regulatory Networks

Large-scale inference of eukaryotic transcription-regulatory networks remains challenging. One underlying reason is that existing algorithms typically ignore crucial regulatory mechanisms, such as RNA degradation and post-transcriptional processing. Here, we describe InfereCLaDR, which incorporates...

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Detalles Bibliográficos
Autores principales: Tchourine, Konstantine, Vogel, Christine, Bonneau, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987223/
https://www.ncbi.nlm.nih.gov/pubmed/29641998
http://dx.doi.org/10.1016/j.celrep.2018.03.048