Upregulation of multiple signaling pathways by Dock5 deletion in epithelial cells

PURPOSE: Rupture of lens cataract (RLC) is a hereditary mouse model that shows spontaneous rupture of the lens at the posterior pole at 45–100 days of age. The responsible gene for this phenotype was identified as Dock5, a guanine nucleotide exchange factor for small GTPase Rac1. This study was perf...

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Detalles Bibliográficos
Autores principales: Xu, Xiaohe, Yoshizaki, Hisayoshi, Ishigaki, Yasuhito, Kubo, Eri, Minato, Hiroshi, Kiyokawa, Etsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987311/
https://www.ncbi.nlm.nih.gov/pubmed/29872253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987311/
https://www.ncbi.nlm.nih.gov/pubmed/29872253

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