Cargando…

GLP-1 Analogue Liraglutide Enhances SP-A Expression in LPS-Induced Acute Lung Injury through the TTF-1 Signaling Pathway

The reduction of pulmonary surfactant (PS) is essential for decreased pulmonary compliance and edema in acute lung injury (ALI). Thyroid transcription factor-1 (TTF-1) plays a major role in the regulation of surfactant protein-A (SP-A), the most abundant protein component of PS. Simultaneously, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Tao, Li, Changyi, Zhang, Xue, Ye, Chunyan, Tang, Shuo, Zhang, Wei, Sun, Jiayang, Huang, Niwen, Wen, Fuqiang, Wang, Daoxin, Deng, Huojin, He, Jing, Qi, Di, Deng, Wang, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987313/
https://www.ncbi.nlm.nih.gov/pubmed/29950925
http://dx.doi.org/10.1155/2018/3601454