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Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice

OBJECTIVES: Human osteoarthritis (OA) is detected only at late stages. Male STR/Ort mice develop knee OA spontaneously with known longitudinal trajectory, offering scope to identify OA predisposing factors. We exploit the lack of overt OA in female STR/Ort and in both sexes of parental, control CBA...

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Detalles Bibliográficos
Autores principales: Javaheri, B., Razi, H., Piles, M., de Souza, R., Chang, Y.-M., Maric-Mur, I., Hopkinson, M., Lee, P.D., Pitsillides, A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987380/
https://www.ncbi.nlm.nih.gov/pubmed/29604337
http://dx.doi.org/10.1016/j.joca.2018.03.008