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A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy

BACKGROUND: Despite the overwhelming number of investigations on AKT, little is known about lncRNA on AKT regulation, especially in GBM cells. METHODS: RNA-binding protein immunoprecipitation assay (RIP) and RNA pulldown were used to confirm the binding of LINC00470 and fused in sarcoma (FUS). Confo...

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Detalles Bibliográficos
Autores principales: Liu, Changhong, Zhang, Yan, She, Xiaoling, Fan, Li, Li, Peiyao, Feng, Jianbo, Fu, Haijuan, Liu, Qing, Liu, Qiang, Zhao, Chunhua, Sun, Yingnan, Wu, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987392/
https://www.ncbi.nlm.nih.gov/pubmed/29866190
http://dx.doi.org/10.1186/s13045-018-0619-z