Cargando…

Whole-genome sequencing reveals highly specific gene targeting by in vitro assembled Cas9-ribonucleoprotein complexes in Aspergillus fumigatus

BACKGROUND: CRISPR/Cas9-based genome editing is quickly becoming a powerful tool within the field of fungal genetics. Adaptation of CRISPR/Cas9 systems are allowing for rapid and highly efficient gene targeting within fungi. We recently reported the adaptation of a simple CRISPR/Cas9 system for gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Abdallah, Qusai, Souza, Ana Camila Oliveira, Martin-Vicente, Adela, Ge, Wenbo, Fortwendel, Jarrod R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987418/
https://www.ncbi.nlm.nih.gov/pubmed/29992034
http://dx.doi.org/10.1186/s40694-018-0057-2