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Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

BACKGROUND: Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth. Nevertheless, MZ twins are sometimes discordant for common complex diseases. The goal of this study is to iden...

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Detalles Bibliográficos
Autores principales: Lyu, Guoliang, Zhang, Chao, Ling, Te, Liu, Rui, Zong, Le, Guan, Yiting, Huang, Xiaoke, Sun, Lei, Zhang, Lijun, Li, Cheng, Nie, Yu, Tao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987557/
https://www.ncbi.nlm.nih.gov/pubmed/29866040
http://dx.doi.org/10.1186/s12864-018-4814-7