Knockdown of asporin affects transforming growth factor-β1-induced matrix synthesis in human intervertebral annulus cells

BACKGROUND/OBJECTIVE: Asporin is associated with osteoarthritis and lumbar disk degeneration. Previous studies in chondrocytes showed that asporin can bind to transforming growth factor-β1 (TGF-β1) and downregulate matrix biosynthesis. However, this has not been studied in intervertebral disk (IVD)...

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Detalles Bibliográficos
Autores principales: Jiang, Xu, Wu, Cheng Ai, Wang, Ying, Shi, Ke-Jian, Jiang, Xiao-Zhou, Zheng, Shan, Tian, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987567/
https://www.ncbi.nlm.nih.gov/pubmed/30035083
http://dx.doi.org/10.1016/j.jot.2016.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987567/
https://www.ncbi.nlm.nih.gov/pubmed/30035083
http://dx.doi.org/10.1016/j.jot.2016.05.011

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