MET alterations detected in blood-derived circulating tumor DNA correlate with bone metastases and poor prognosis

BACKGROUND: We analyzed clinical associations of MET alterations in the plasma of patients with diverse malignancies. METHODS: Digital sequencing of circulating tumor DNA (ctDNA) (54–70 genes) was performed in 438 patients; 263 patients also had tissue sequencing (182–315 genes). The most represente...

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Detalles Bibliográficos
Autores principales: Ikeda, Sadakatsu, Schwaederle, Maria, Mohindra, Mandakini, Fontes Jardim, Denis L., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987577/
https://www.ncbi.nlm.nih.gov/pubmed/29866143
http://dx.doi.org/10.1186/s13045-018-0610-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987577/
https://www.ncbi.nlm.nih.gov/pubmed/29866143
http://dx.doi.org/10.1186/s13045-018-0610-8

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