Aqp0a Regulates Suture Stability in the Zebrafish Lens

PURPOSE: To investigate the roles of Aquaporin 0a (Aqp0a) and Aqp0b in zebrafish lens development and transparency. METHODS: CRISPR/Cas9 gene editing was used to generate loss-of-function deletions in zebrafish aqp0a and/or aqp0b. Wild type (WT), single mutant, and double mutant lenses were analyzed...

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Detalles Bibliográficos
Autores principales: Vorontsova, Irene, Gehring, Ines, Hall, James E., Schilling, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987579/
https://www.ncbi.nlm.nih.gov/pubmed/30025131
http://dx.doi.org/10.1167/iovs.18-24044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987579/
https://www.ncbi.nlm.nih.gov/pubmed/30025131
http://dx.doi.org/10.1167/iovs.18-24044

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