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Aqp0a Regulates Suture Stability in the Zebrafish Lens
PURPOSE: To investigate the roles of Aquaporin 0a (Aqp0a) and Aqp0b in zebrafish lens development and transparency. METHODS: CRISPR/Cas9 gene editing was used to generate loss-of-function deletions in zebrafish aqp0a and/or aqp0b. Wild type (WT), single mutant, and double mutant lenses were analyzed...
Autores principales: | Vorontsova, Irene, Gehring, Ines, Hall, James E., Schilling, Thomas F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987579/ https://www.ncbi.nlm.nih.gov/pubmed/30025131 http://dx.doi.org/10.1167/iovs.18-24044 |
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