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Gene expression profiling in the developing secondary palate in the absence of Tbx1 function

BACKGROUND: Microdeletion of chromosome 22q11 is associated with significant developmental anomalies, including disruption of the cardiac outflow tract, thymic/parathyroid aplasia and cleft palate. Amongst the genes within this region, TBX1 is a major candidate for many of these developmental defect...

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Detalles Bibliográficos
Autores principales: Zoupa, Maria, Xavier, Guilherme Machado, Bryan, Stephanie, Theologidis, Ioannis, Arno, Matthew, Cobourne, Martyn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987606/
https://www.ncbi.nlm.nih.gov/pubmed/29866044
http://dx.doi.org/10.1186/s12864-018-4782-y