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Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment

BACKGROUND: Novel therapeutic approaches are required to treat ovarian cancer and dependency on glycolysis may provide new targets for treatment. This study sought to investigate the variation of expression of molecular components (GLUT1, HKII, PKM2, LDHA) of the glycolytic pathway in ovarian cancer...

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Detalles Bibliográficos
Autores principales: Xintaropoulou, Chrysi, Ward, Carol, Wise, Alan, Queckborner, Suzanna, Turnbull, Arran, Michie, Caroline O., Williams, Alistair R. W., Rye, Tzyvia, Gourley, Charlie, Langdon, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987622/
https://www.ncbi.nlm.nih.gov/pubmed/29866066
http://dx.doi.org/10.1186/s12885-018-4521-4