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Human antigen R enhances the epithelial-mesenchymal transition via regulation of ZEB-1 in the human airway epithelium

BACKGROUND: Increasing evidence suggests that human antigen R (HuR) is involved in the epithelial-mesenchymal transition (EMT) process of several diseases. However, the role of HuR in EMT in the airway epithelial cells of patients with COPD remains unclear. METHODS: BEAS-2B cells were cultured and t...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Gu, Xianmin, Wu, Nan, Zhang, Pengju, Liu, Yi, Jiang, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987655/
https://www.ncbi.nlm.nih.gov/pubmed/29866111
http://dx.doi.org/10.1186/s12931-018-0805-0