Moderate Exercise Suppresses NF-κB Signaling and Activates the SIRT1-AMPK-PGC1α Axis to Attenuate Muscle Loss in Diabetic db/db Mice

The clear mechanism of moderate exercise training (Ex) in attenuating muscle loss remains elusive in diabetes. We investigated the effects of moderate exercise training on diabetes-induced nuclear factor-κB (NF-κB) activation and mitochondrial dysfunction. Skeletal muscle size and atrophy signaling...

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Detalles Bibliográficos
Autores principales: Liu, Hung-Wen, Chang, Sue-Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987703/
https://www.ncbi.nlm.nih.gov/pubmed/29896118
http://dx.doi.org/10.3389/fphys.2018.00636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987703/
https://www.ncbi.nlm.nih.gov/pubmed/29896118
http://dx.doi.org/10.3389/fphys.2018.00636

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