Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics

Single-headed myosin 1 has been identified in neurons, but its function in these cells is still unclear. We demonstrate that depletion of myosin 1b (Myo1b), inhibition of its motor activity, or its binding to phosphoinositides impairs the formation of the axon, whereas overexpression of Myo1b increa...

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Detalles Bibliográficos
Autores principales: Iuliano, Olga, Yoshimura, Azumi, Prospéri, Marie-Thérèse, Martin, René, Knölker, Hans-Joachim, Coudrier, Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987710/
https://www.ncbi.nlm.nih.gov/pubmed/29588377
http://dx.doi.org/10.1083/jcb.201703205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987710/
https://www.ncbi.nlm.nih.gov/pubmed/29588377
http://dx.doi.org/10.1083/jcb.201703205

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