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Hsp40/70/110 chaperones adapt nuclear protein quality control to serve cytosolic clients

Misfolded cytosolic proteins are degraded by the ubiquitin proteasome system through quality control (QC) pathways defined by E3 ubiquitin ligases and associated chaperones. Although they work together as a comprehensive system to monitor cytosolic protein folding, their respective contributions rem...

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Detalles Bibliográficos
Autores principales: Prasad, Rupali, Xu, Chengchao, Ng, Davis T.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987712/
https://www.ncbi.nlm.nih.gov/pubmed/29653997
http://dx.doi.org/10.1083/jcb.201706091