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Hsp40/70/110 chaperones adapt nuclear protein quality control to serve cytosolic clients
Misfolded cytosolic proteins are degraded by the ubiquitin proteasome system through quality control (QC) pathways defined by E3 ubiquitin ligases and associated chaperones. Although they work together as a comprehensive system to monitor cytosolic protein folding, their respective contributions rem...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987712/ https://www.ncbi.nlm.nih.gov/pubmed/29653997 http://dx.doi.org/10.1083/jcb.201706091 |