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EB1 binding restricts STIM1 translocation to ER–PM junctions and regulates store-operated Ca(2+) entry
The endoplasmic reticulum (ER) Ca(2+) sensor STIM1 forms oligomers and translocates to ER–plasma membrane (PM) junctions to activate store-operated Ca(2+) entry (SOCE) after ER Ca(2+) depletion. STIM1 also interacts with EB1 and dynamically tracks microtubule (MT) plus ends. Nevertheless, the role o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987725/ https://www.ncbi.nlm.nih.gov/pubmed/29563214 http://dx.doi.org/10.1083/jcb.201711151 |