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EB1 binding restricts STIM1 translocation to ER–PM junctions and regulates store-operated Ca(2+) entry

The endoplasmic reticulum (ER) Ca(2+) sensor STIM1 forms oligomers and translocates to ER–plasma membrane (PM) junctions to activate store-operated Ca(2+) entry (SOCE) after ER Ca(2+) depletion. STIM1 also interacts with EB1 and dynamically tracks microtubule (MT) plus ends. Nevertheless, the role o...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Lun, Chen, Yu-Ju, Quintanilla, Carlo Giovanni, Hsieh, Ting-Sung, Liou, Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987725/
https://www.ncbi.nlm.nih.gov/pubmed/29563214
http://dx.doi.org/10.1083/jcb.201711151