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Crystal structure of an inactive variant of the quorum-sensing master regulator HapR from the protease-deficient non-O1, non-O139 Vibrio cholerae strain V2

HapR is a TetR-family transcriptional regulator that controls quorum sensing in Vibrio cholerae, the causative agent of cholera. HapR regulates the expression of hemagglutinin protease, virulence and biofilm genes. The crystal structure of wild-type HapR from V. cholerae strain O1 El Tor C6706 has p...

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Detalles Bibliográficos
Autores principales: Cruite, Justin, Succo, Patrick, Raychaudhuri, Saumya, Kull, F. Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987740/
https://www.ncbi.nlm.nih.gov/pubmed/29870016
http://dx.doi.org/10.1107/S2053230X18006519