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Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1
BACKGROUND: Obesity was a recognized risk factor for the development and progression of hepatocellular carcinoma (HCC). However, the effects and mechanisms by which obesity promotes HCC metastasis remain poorly understood. MATERIALS AND METHODS: We cultured adipocyte induced by preadipocyte 3T3-L1 i...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987752/ https://www.ncbi.nlm.nih.gov/pubmed/29910623 http://dx.doi.org/10.2147/OTT.S162978 |