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Optimization of a combined wet milling process in order to produce poly(vinyl alcohol) stabilized nanosuspension
PURPOSE: The article reports a wet milling process, where the planetary ball mill was combined with pearl milling technology to reach nanosize range of meloxicam (Mel; 100–500 nm). The main purpose was to increase the dissolution rate and extent of a poorly water-soluble Mel as nonsteroidal anti-inf...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987755/ https://www.ncbi.nlm.nih.gov/pubmed/29910603 http://dx.doi.org/10.2147/DDDT.S159965 |