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Effects of the combination of As(2)O(3) and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1
CONTEXT: Previous studies have demonstrated that 3′-azido-3′-deoxythymidine (AZT) and arsenic trioxide (As(2)O(3)), traditional chemotherapy agents, can synergically inhibit the growth of hepatocellular carcinoma cells. However, the molecular mechanisms underlying As(2)O(3) and AZT anti-hepatoma act...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987793/ https://www.ncbi.nlm.nih.gov/pubmed/29910624 http://dx.doi.org/10.2147/OTT.S155169 |