GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever

Pyroptosis is an inflammasome-induced lytic cell death mode, the physiological role of which in chronic inflammatory diseases is unknown. Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease worldwide, affecting an estimated 150,000 patients. The disease is caused...

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Detalles Bibliográficos
Autores principales: Kanneganti, Apurva, Malireddi, R.K. Subbarao, Saavedra, Pedro H.V., Vande Walle, Lieselotte, Van Gorp, Hanne, Kambara, Hiroto, Tillman, Heather, Vogel, Peter, Luo, Hongbo R., Xavier, Ramnik J., Chi, Hongbo, Lamkanfi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987922/
https://www.ncbi.nlm.nih.gov/pubmed/29793924
http://dx.doi.org/10.1084/jem.20172060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987922/
https://www.ncbi.nlm.nih.gov/pubmed/29793924
http://dx.doi.org/10.1084/jem.20172060

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