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GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever
Pyroptosis is an inflammasome-induced lytic cell death mode, the physiological role of which in chronic inflammatory diseases is unknown. Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease worldwide, affecting an estimated 150,000 patients. The disease is caused...
Autores principales: | Kanneganti, Apurva, Malireddi, R.K. Subbarao, Saavedra, Pedro H.V., Vande Walle, Lieselotte, Van Gorp, Hanne, Kambara, Hiroto, Tillman, Heather, Vogel, Peter, Luo, Hongbo R., Xavier, Ramnik J., Chi, Hongbo, Lamkanfi, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987922/ https://www.ncbi.nlm.nih.gov/pubmed/29793924 http://dx.doi.org/10.1084/jem.20172060 |
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