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Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity

Understanding pathways that promote HIV-1 broadly neutralizing antibody (bnAb) induction is crucial to advance bnAb-based vaccines. We recently demarcated host, viral, and disease parameters associated with bnAb development in a large HIV-1 cohort screen. By establishing comprehensive antibody signa...

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Detalles Bibliográficos
Autores principales: Kadelka, Claus, Liechti, Thomas, Ebner, Hanna, Schanz, Merle, Rusert, Peter, Friedrich, Nikolas, Stiegeler, Emanuel, Braun, Dominique L., Huber, Michael, Scherrer, Alexandra U., Weber, Jacqueline, Uhr, Therese, Kuster, Herbert, Misselwitz, Benjamin, Cavassini, Matthias, Bernasconi, Enos, Hoffmann, Matthias, Calmy, Alexandra, Battegay, Manuel, Rauch, Andri, Yerly, Sabine, Aubert, Vincent, Klimkait, Thomas, Böni, Jürg, Kouyos, Roger D., Günthard, Huldrych F., Trkola, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987927/
https://www.ncbi.nlm.nih.gov/pubmed/29794117
http://dx.doi.org/10.1084/jem.20180246