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Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia
Peripherally derived macrophages infiltrate the brain after bone marrow transplantation and during central nervous system (CNS) inflammation. It was initially suggested that these engrafting cells were newly derived microglia and that irradiation was essential for engraftment to occur. However, it r...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987928/ https://www.ncbi.nlm.nih.gov/pubmed/29643186 http://dx.doi.org/10.1084/jem.20180247 |