Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia

Peripherally derived macrophages infiltrate the brain after bone marrow transplantation and during central nervous system (CNS) inflammation. It was initially suggested that these engrafting cells were newly derived microglia and that irradiation was essential for engraftment to occur. However, it r...

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Detalles Bibliográficos
Autores principales: Cronk, James C., Filiano, Anthony J., Louveau, Antoine, Marin, Ioana, Marsh, Rachel, Ji, Emily, Goldman, Dylan H., Smirnov, Igor, Geraci, Nicholas, Acton, Scott, Overall, Christopher C., Kipnis, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987928/
https://www.ncbi.nlm.nih.gov/pubmed/29643186
http://dx.doi.org/10.1084/jem.20180247

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