c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells

The transcription factor c-Maf induces the anti-inflammatory cytokine IL-10 in CD4(+) T cells in vitro. However, the global effects of c-Maf on diverse immune responses in vivo are unknown. Here we show that c-Maf regulates IL-10 production in CD4(+) T cells in T(H)1 (malaria), T(H)2 (allergy) and T...

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Detalles Bibliográficos
Autores principales: Gabryšová, Leona, Alvarez-Martinez, Marisol, Luisier, Raphaëlle, Cox, Luke S., Sodenkamp, Jan, Hosking, Caroline, Pérez-Mazliah, Damián, Whicher, Charlotte, Kannan, Yashaswini, Potempa, Krzysztof, Wu, Xuemei, Bhaw, Leena, Wende, Hagen, Sieweke, Michael H., Elgar, Greg, Wilson, Mark, Briscoe, James, Metzis, Vicki, Langhorne, Jean, Luscombe, Nicholas M., O’Garra, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988041/
https://www.ncbi.nlm.nih.gov/pubmed/29662170
http://dx.doi.org/10.1038/s41590-018-0083-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988041/
https://www.ncbi.nlm.nih.gov/pubmed/29662170
http://dx.doi.org/10.1038/s41590-018-0083-5

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