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Optical Structural Analysis of Individual α‐Synuclein Oligomers

Small aggregates of misfolded proteins play a key role in neurodegenerative disorders. Such species have proved difficult to study due to the lack of suitable methods capable of resolving these heterogeneous aggregates, which are smaller than the optical diffraction limit. We demonstrate here an all...

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Detalles Bibliográficos
Autores principales: Varela, Juan A., Rodrigues, Margarida, De, Suman, Flagmeier, Patrick, Gandhi, Sonia, Dobson, Christopher M., Klenerman, David, Lee, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988047/
https://www.ncbi.nlm.nih.gov/pubmed/29342318
http://dx.doi.org/10.1002/anie.201710779