Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL)

INTRODUCTION: Roux-en-Y gastric bypass (GBP) is associated with changes in cardiometabolic risk factors and bioavailability of drugs, but whether these changes are induced by calorie restriction, the weight loss or surgery per se, remains uncertain. The COCKTAIL study was designed to disentangle the...

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Detalles Bibliográficos
Autores principales: Hjelmesæth, Jøran, Åsberg, Anders, Andersson, Shalini, Sandbu, Rune, Robertsen, Ida, Johnson, Line Kristin, Angeles, Philip Carlo, Hertel, Jens Kristoffer, Skovlund, Eva, Heijer, Maria, Ek, Anna-Lena, Krogstad, Veronica, Karlsen, Tor-Ivar, Christensen, Hege, Andersson, Tommy B, Karlsson, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988193/
https://www.ncbi.nlm.nih.gov/pubmed/29844102
http://dx.doi.org/10.1136/bmjopen-2018-021878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988193/
https://www.ncbi.nlm.nih.gov/pubmed/29844102
http://dx.doi.org/10.1136/bmjopen-2018-021878

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