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Reprogramming of Chromatin Accessibility in Somatic Cell Nuclear Transfer Is DNA Replication Independent

Mammalian oocytes have the ability to reset the transcriptional program of differentiated somatic cells into that of totipotent embryos through somatic cell nuclear transfer (SCNT). However, the mechanisms underlying SCNT-mediated reprogramming are largely unknown. To understand the mechanisms gover...

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Detalles Bibliográficos
Autores principales: Djekidel, Mohamed Nadhir, Inoue, Azusa, Matoba, Shogo, Suzuki, Tsukasa, Zhang, Chunxia, Lu, Falong, Jiang, Lan, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988247/
https://www.ncbi.nlm.nih.gov/pubmed/29768195
http://dx.doi.org/10.1016/j.celrep.2018.04.036