The PKC-β selective inhibitor, Enzastaurin, impairs memory in middle-aged rats

Enzastaurin is a Protein Kinase C-β selective inhibitor that was developed to treat cancers. Protein Kinase C-β is an important enzyme for a variety of neuronal functions; in particular, previous rodent studies have reported deficits in spatial and fear-conditioned learning and memory with lower lev...

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Detalles Bibliográficos
Autores principales: Willeman, Mari N., Mennenga, Sarah E., Siniard, Ashley L., Corneveaux, Jason J., De Both, Matt, Hewitt, Lauren T., Tsang, Candy W. S., Caselli, Jason, Braden, B. Blair, Bimonte-Nelson, Heather A., Huentelman, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988320/
https://www.ncbi.nlm.nih.gov/pubmed/29870545
http://dx.doi.org/10.1371/journal.pone.0198256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988320/
https://www.ncbi.nlm.nih.gov/pubmed/29870545
http://dx.doi.org/10.1371/journal.pone.0198256

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