Oligomerization of a molecular chaperone modulates its activity

Molecular chaperones alter the folding properties of cellular proteins via mechanisms that are not well understood. Here, we show that Trigger Factor (TF), an ATP-independent chaperone, exerts strikingly contrasting effects on the folding of non-native proteins as it transitions between a monomeric...

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Detalles Bibliográficos
Autores principales: Saio, Tomohide, Kawagoe, Soichiro, Ishimori, Koichiro, Kalodimos, Charalampos G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988418/
https://www.ncbi.nlm.nih.gov/pubmed/29714686
http://dx.doi.org/10.7554/eLife.35731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988418/
https://www.ncbi.nlm.nih.gov/pubmed/29714686
http://dx.doi.org/10.7554/eLife.35731

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