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Oligomerization of a molecular chaperone modulates its activity
Molecular chaperones alter the folding properties of cellular proteins via mechanisms that are not well understood. Here, we show that Trigger Factor (TF), an ATP-independent chaperone, exerts strikingly contrasting effects on the folding of non-native proteins as it transitions between a monomeric...
Autores principales: | Saio, Tomohide, Kawagoe, Soichiro, Ishimori, Koichiro, Kalodimos, Charalampos G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988418/ https://www.ncbi.nlm.nih.gov/pubmed/29714686 http://dx.doi.org/10.7554/eLife.35731 |
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