Haptoglobin 2-2 genotype is associated with presence and progression of MRI depicted atherosclerotic intraplaque hemorrhage

BACKGROUND: Atherosclerotic intraplaque hemorrhage (IPH) is a source of free hemoglobin that binds the haptoglobin protein and forms a complex cleared by CD163 macrophages. Compared to the other common haptoglobin genotypes, hemoglobin-haptoglobin2-2 complex has the lowest affinity for tissue macrop...

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Detalles Bibliográficos
Autores principales: Marvasti, Tina Binesh, Moody, Alan R., Singh, Navneet, Maraj, Tishan, Tyrrell, Pascal, Afshin, Mariam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988477/
https://www.ncbi.nlm.nih.gov/pubmed/29876508
http://dx.doi.org/10.1016/j.ijcha.2017.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988477/
https://www.ncbi.nlm.nih.gov/pubmed/29876508
http://dx.doi.org/10.1016/j.ijcha.2017.11.003

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