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Haptoglobin 2-2 genotype is associated with presence and progression of MRI depicted atherosclerotic intraplaque hemorrhage
BACKGROUND: Atherosclerotic intraplaque hemorrhage (IPH) is a source of free hemoglobin that binds the haptoglobin protein and forms a complex cleared by CD163 macrophages. Compared to the other common haptoglobin genotypes, hemoglobin-haptoglobin2-2 complex has the lowest affinity for tissue macrop...
Autores principales: | Marvasti, Tina Binesh, Moody, Alan R., Singh, Navneet, Maraj, Tishan, Tyrrell, Pascal, Afshin, Mariam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988477/ https://www.ncbi.nlm.nih.gov/pubmed/29876508 http://dx.doi.org/10.1016/j.ijcha.2017.11.003 |
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