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Set up of a protocol for rat plasma peptidomics in hemorrhagic shock model in presence of heparin

A preliminary mass spectrometry based shotgun protocol was set up to compare the peptidome of plasma samples from healthy and hemorrhagic shock rats with the aim of verifying the possible role of uncontrolled proteolytic activity in circulatory shock. Since the hemorrhagic shock model requires hepar...

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Detalles Bibliográficos
Autores principales: Maffioli, Elisa, Aletti, Federico, Santagata, Fabiana, Negri, Armando, Santamaria, Marco H., De Lano, Frank A., Kistler, Erik B., Schmid-Schönbein, Geert W., Tedeschi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988501/
https://www.ncbi.nlm.nih.gov/pubmed/29900112
http://dx.doi.org/10.1016/j.euprot.2016.03.004